Read Our Complete Guide to Next-Generation ADCs To Discover

  • Holistic ADC Design: Learn how each component, antibody, linker and payload shapes overall efficacy
  • Payload Optimization: Strategies to enhance potency, safety and selectivity through a payload-focused approach
  • Antigen & Linker Selection: Complementary antigen/payload pairs & linker chemistry roles in therapeutic precision
  • DMPK & Pharmacology Insight: DMPK profile optimization & integrated translational design for clinical performance
  • Future Outlook: Where is the field heading and how do we get there?

A Preview Inside 

ADC eBook Contents
ADC eBook Chapter 3 Turning Small Molecules into Payloads

Conventionally, ADC development has taken a large-molecule focussed pathway, yet this approach isn’t addressing the current clinical challenges.

Next generation ADC development will require a more holistic pathway, relying on medicinal chemistry for optimisation of more selective payloads, linkers and conjugation strategies, demanding a truly integrated, cross-disciplinary approach.

Discover how smarter linkers and a payload-focused strategy is reshaping the future of ADCs, and how you can stay ahead of the curve

To learn more about Sygnature Discovery's Expertise in Antibody Drug Conjugates, please [click here]