Everything You Need to Know about ADCs: A Payload-Focused Approach
ADC design is complex, from payload toxicity and linker instability to antigen specificity.
This eBook combines cross-disciplinary expertise and proven strategies to help you navigate a NewPath forward, accelerating the creation of safer, more effective therapeutics.
Read Our Complete Guide to Next-Generation ADCs To Discover
- Holistic ADC Design: Learn how each component, antibody, linker and payload shapes overall efficacy
- Payload Optimization: Strategies to enhance potency, safety and selectivity through a payload-focused approach
- Antigen & Linker Selection: Complementary antigen/payload pairs & linker chemistry roles in therapeutic precision
- DMPK & Pharmacology Insight: DMPK profile optimization & integrated translational design for clinical performance
- Future Outlook: Where is the field heading and how do we get there?
Conventionally seen as the domain of large-molecule specialists, delivering next generation ADCs will also rely on small-molecule focused optimization of payloads, linkers and conjugation strategies, demanding a truly integrated, cross-disciplinary approach.
Discover how smarter linkers and a payload-focused strategy is reshaping the future of ADCs, and how you can stay ahead of the curve