Project Guidance With In Silico and PBPK Modelling
Working with your full project team, Sygnature Discovery’s experienced in Silico modelling, PBPK modelling and simulation team provides guidance throughout the lifetime of your project.
In Silico modelling and PBPK modelling – Gold standard modelling
Sygnature Discovery uses the GastroPlusTM software package that simulates absorption, distribution, metabolism and elimination in humans and animals from a range of dose routes including oral, intravenous, inhaled, ocular and dermal.
This enables data integration within the context of a virtual animal or human model. Having this in silico modelling understanding can help us make faster and more informed development decisions.
It has been identified as the number one commercially ranked program for in vitro-in vivo extrapolation and has been the focus of several publications from the FDA.
Delivering for our customers - a proven track record
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