Drive Compounds Closer To The Clinic With In Vivo Pharmacology Services
Validating the effectiveness of novel therapeutics through in vivo studies represents a pivotal phase within the realm of drug discovery. As a dedicated provider specialising in in vivo pharmacology, we possess the expertise to design and execute robust experimental animal models that drive your compounds closer to clinical fruition. Our approach is a blend of well-established disease models and bespoke model development services, meticulously customised to align with the demands of your unique project. We take pride in our adaptive and transparent work ethos, nurturing collaborative partnerships with our valued clients.
IVP Services
Our highly qualified in vivo pharmacology staff are uniquely positioned within our integrated drug discovery teams. This enables us to maximise multidisciplinary study support and ultimately accelerate your drug discovery efforts.
Our experts specialise in four key areas:
CNS Disorder Models
We have a unique and extensive experience in diseases of the CNS including Psychiatric Disorders, which can be a particularly challenging field for drug development.
Metabolic Models
Our history of performing high quality in vivo pharmacology investigations in the metabolic space ranging from insulin resistance to diabetic complications means we are well equipped to guide the right choice of translatable models and necessary endpoints.
Fibrosis and Inflammation Models
We have established a range of in vivo and ex vivo pharmacology models, which enables careful assessment of drug candidates.
In Vivo Oncology Models
Our Translational Oncology team offers bespoke, high quality in vivo pharmacology services to customers.
Delivering for our customers - a proven track record
- 48 pre-clinical candidates delivered
- 27 already progressed to clinical trials (>50%)
- Sygnature Discovery co-inventors named on >170 client patent applications
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Discover your next project's potential
Animal welfare is our top priority at Sygnature Discovery. We employ the highest standards of animal care and implement the principles of the 3Rs (replacement, reduction and refinement) to all studies, and have worked hard to foster a culture of compassion and care towards all our animals.